Reaktionsgleichung
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][N:11]2[CH:15]=[CH:14][N:13]=[CH:12]2)=[CH:4][CH:3]=1.Cl[CH2:17][C:18]1[N:19]=[C:20]([C:23]2[O:24][CH:25]=[CH:26][CH:27]=2)[O:21][CH:22]=1>>[O:24]1[CH:25]=[CH:26][CH:27]=[C:23]1[C:20]1[O:21][CH:22]=[C:18]([CH2:17][O:1][C:2]2[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][N:11]3[CH:15]=[CH:14][N:13]=[CH:12]3)=[CH:4][CH:3]=2)[N:19]=1Komponenten
3
Versuchsvorschrift
In substantially the same manner as in Working Example 109, 1-[3-(4-hydroxyphenyl)propyl]imidazole was allowed to react with 4-chloromethyl-2-(2-furyl)oxazole to give 2-(2-furyl)-4-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]oxazole. The yield was 31%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 92-93° C.
Quellen und Nachweise
- ORD-Eintrag
- ord-fdd8f8e2ef8d4e82af015f3fac9cc0f2
- Quelldatensatz
- uspto-grants-2001_04
- Patentnummer
- US06211215B1
Verknüpfte Notizen
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