1-[3-(4-Hydroxyphenyl)propyl]imidazole → HCID 22009869, Verbindung
Reaktionsgleichung
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][N:11]2[CH:15]=[CH:14][N:13]=[CH:12]2)=[CH:4][CH:3]=1.Cl[CH2:17][C:18]1[CH:19]=[CH:20][C:21]2[O:25][C:24]([C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)=[N:23][C:22]=2[CH:32]=1>>[N:11]1([CH2:10][CH2:9][CH2:8][C:5]2[CH:6]=[CH:7][C:2]([O:1][CH2:17][C:18]3[CH:19]=[CH:20][C:21]4[O:25][C:24]([C:26]5[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=5)=[N:23][C:22]=4[CH:32]=3)=[CH:3][CH:4]=2)[CH:15]=[CH:14][N:13]=[CH:12]1Komponenten
3
Versuchsvorschrift
In substantially the same manner as in Working Example 109, 1-[3-(4-hydroxyphenyl)propyl]imidazole was allowed to react with 5-chloromethyl-2-phenylbezoxazole to give 5-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]-2-phenylbenzoxazole. The yield was 67%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 137-138° C.
Quellen und Nachweise
- ORD-Eintrag
- ord-40c57d5a949b4520bf6e3f2b67378c5b
- Quelldatensatz
- uspto-grants-2001_04