HCID 22009623, Verbindung → HCID 22009771, Verbindung
Reaktionsgleichung
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][N:11]2[CH:15]=[CH:14][N:13]=[CH:12]2)=[CH:4][CH:3]=1.Cl[CH2:17][C:18]1[N:19]=[C:20]([C:23]2[S:24][CH:25]=[C:26]([Cl:28])[CH:27]=2)[O:21][CH:22]=1>>[Cl:28][C:26]1[CH:27]=[C:23]([C:20]2[O:21][CH:22]=[C:18]([CH2:17][O:1][C:2]3[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][N:11]4[CH:15]=[CH:14][N:13]=[CH:12]4)=[CH:4][CH:3]=3)[N:19]=2)[S:24][CH:25]=1Komponenten
3
Versuchsvorschrift
In substantially the same manner as in Working Example 72, 1-[3-(4-hydroxyphenyl)propyl]imidazole was allowed to react with 4-chloromethyl-2-(4-chloro-2-thienyl)oxazole to give 2-(4-chloro-2-thienyl)-4-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]oxazole. The yield was 80%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 69-70° C.
Quellen und Nachweise
- ORD-Eintrag
- ord-6c21ae9a1ce94cb0970f6957278a5dbb
- Quelldatensatz
- uspto-grants-2001_04