HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
[4-(2-Amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(4-fluoro-phenyl)-amine → HCID 10291242, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | [4-(2-Amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(4-fluoro-phenyl)-amine | HCID 9857535 | — |
| Edukt | 2-{4-Methyl-5-[2-(3-nitro-phenylamino)-pyrimidin-4-yl]-thiazol-2-ylamino}-ethanol | HCID 10109809 | — |
| Produkt | HCID 10291242 | HCID 10291242 | — |
Reaktionsschritte
This compound was prepared from [4-(2-amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(4-fluoro-phenyl)-amine in a manner analogous to that described for compound [58]. 1H-NMR (DMSO-d6) δ: 2.44 (s, 3H, CH3), 3.54 (m, 2H, CH2), 4.78 (m, 2H, CH2), 6.87 (d, 1H, J=5.2 Hz, pyrimidinyl-H), 7.09 (m, 2H, Ph-H), 7.75 (m, 2H, Ph-H), 8.30 (d, 1H, J=5.2 Hz, pyrimidinyl-H), 8.11 (m, 1H, NH), 9.43 (s, 1H, NH). DE MALDI-TOF MS: [M+H]+=345.79 (C16H16FN5OS requires 345.40).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07427627B2 |
| Quelldatensatz | uspto-grants-2008_09 |
| ORD ID | ord-cc43d9634c2e4647b6cfa6e32a115909 |
| Quellennotiz | uspto-grants-2008_09 |