Ethyl 2-(4-hydroxyphenoxy)-2-methylpropanoate → Ethyl 2-methyl-2-[4-(6-chloroquinolin-2-yloxy)phenoxy]-propionate

HRID 326039

Reaktionsgleichung

Reaktionsgleichung von HRID 326039
Cl[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:12])[CH:8]=2)[N:3]=1.[CH3:13][C:14]([O:21][C:22]1[CH:27]=[CH:26][C:25]([OH:28])=[CH:24][CH:23]=1)([CH3:20])[C:15]([O:17][CH2:18][CH3:19])=[O:16]>>[CH3:20][C:14]([O:21][C:22]1[CH:23]=[CH:24][C:25]([O:28][C:2]2[CH:11]=[CH:10][C:9]3[C:4](=[CH:5][CH:6]=[C:7]([Cl:12])[CH:8]=3)[N:3]=2)=[CH:26][CH:27]=1)([CH3:13])[C:15]([O:17][CH2:18][CH3:19])=[O:16]

Komponenten

3

Edukt 2

HCID 181741Ethyl 2-(4-hydroxyphenoxy)-2-methylpropanoateHCID 6075022,6-Dichloroquinoline

Produkt 1

HCID 20461951Ethyl 2-methyl-2-[4-(6-chloroquinolin-2-yloxy)phenoxy]-propionate

Versuchsvorschrift

Ethyl 2-methyl-2-[4-(6-chloroquinolin-2-yloxy)phenoxy]-propionate (36) was prepared from 2,6-dichloroquinoline and ethyl 2-methyl-2-(4-hydroxyphenoxy)propionate following essentially the same procedure as that described in Example 1. The product was isolated after chromatography as a low melting point solid. Mass spectrum (m/e): 385 (parent ion; 30%); 312 (35%); 271 (100%); 270 (100).

Aufarbeitung

  1. customThe product was isolated after chromatography as a low melting point solid

Quellen und Nachweise

ORD-Eintrag
ord-1a94effe0ac8457cbaabccc480144319
Quelldatensatz
uspto-grants-1984_04
Patentnummer
US04444584

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