HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one → 2-Ethyl-7-(3-pyridyl)[1,2,4]triazolo[1,5-a]pyrimidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one | HCID 567033 | — |
| Edukt | 5-ethyl-1H-1,2,4-triazol-3-amine | HCID 1714204 | — |
| Lösungsmittel | Acetic Acid | HCID 176 | — |
| Produkt | 2-Ethyl-7-(3-pyridyl)[1,2,4]triazolo[1,5-a]pyrimidine | HCID 13309049 | 67,1% |
Reaktionsschritte
A mixture of 1.12 g of 3-amino-5-ethyl-1,2,4-triazole and 1.76 g of 3-dimethylamino-1-(3-pyridyl)-2-propene-1-one in 25 ml of glacial acetic acid was refluxed for six hours and the procedure of Example 1 was continued to give 1.51 g of the desired product as colorless needles, mp 147°-149° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04444774 |
| Quelldatensatz | uspto-grants-1984_04 |
| ORD ID | ord-31677377b23d444bafe5892f8d4658f0 |
| Quellennotiz | uspto-grants-1984_04 |