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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 326092Erstellt: 23. Oktober 2026

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one → 2-Ethyl-7-(3-pyridyl)[1,2,4]triazolo[1,5-a]pyrimidine

https://huagongshe.com/de/reaction/326092

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-oneHCID 567033—
Edukt5-ethyl-1H-1,2,4-triazol-3-amineHCID 1714204—
LösungsmittelAcetic AcidHCID 176—
Produkt2-Ethyl-7-(3-pyridyl)[1,2,4]triazolo[1,5-a]pyrimidineHCID 1330904967,1%

Reaktionsschritte

A mixture of 1.12 g of 3-amino-5-ethyl-1,2,4-triazole and 1.76 g of 3-dimethylamino-1-(3-pyridyl)-2-propene-1-one in 25 ml of glacial acetic acid was refluxed for six hours and the procedure of Example 1 was continued to give 1.51 g of the desired product as colorless needles, mp 147°-149° C.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04444774
Quelldatensatzuspto-grants-1984_04
ORD IDord-31677377b23d444bafe5892f8d4658f0
Quellennotizuspto-grants-1984_04