HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-(5-Carboxypent-4-enyl)-imidazo[1,5-a]pyridine → Pirmagrel
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-(5-Carboxypent-4-enyl)-imidazo[1,5-a]pyridine | HCID 53808053 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | Pirmagrel | HCID 55390 | — |
Reaktionsschritte
To a solution of 150 mg of 5-(5-carboxypent-4-enyl)-imidazo[1,5-a]pyridine in 7 ml methanol is added 100 mg of 10% palladium on carbon as catalyst. The reaction mixture is hydrogenated at atmospheric pressure for 3 hours. The catalyst is removed by filtration and the solvent evaporated under reduced pressure to yield 5-(5-carboxypentyl)-imidazo[1,5-a]pyridine melting at 144°-7°, and identical to the product of Example 2.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04444775 |
| Quelldatensatz | uspto-grants-1984_04 |
| ORD ID | ord-4e20b28dbeee41708cc00e3314c66d4b |
| Quellennotiz | uspto-grants-1984_04 |