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HRID 326129Erstellt: 23. Oktober 2026

5-(5-Carboxypent-4-enyl)-imidazo[1,5-a]pyridine → Pirmagrel

https://huagongshe.com/de/reaction/326129

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt5-(5-Carboxypent-4-enyl)-imidazo[1,5-a]pyridineHCID 53808053—
KatalysatorPalladiumHCID 23938—
LösungsmittelMethanolHCID 887—
ProduktPirmagrelHCID 55390—

Reaktionsschritte

To a solution of 150 mg of 5-(5-carboxypent-4-enyl)-imidazo[1,5-a]pyridine in 7 ml methanol is added 100 mg of 10% palladium on carbon as catalyst. The reaction mixture is hydrogenated at atmospheric pressure for 3 hours. The catalyst is removed by filtration and the solvent evaporated under reduced pressure to yield 5-(5-carboxypentyl)-imidazo[1,5-a]pyridine melting at 144°-7°, and identical to the product of Example 2.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04444775
Quelldatensatzuspto-grants-1984_04
ORD IDord-4e20b28dbeee41708cc00e3314c66d4b
Quellennotizuspto-grants-1984_04