1-Methyl-2-imidazolecarboxaldehyde → [5-(7-amino[1,3]thiazolo[5,4-d]pyrimidin-2-yl)-1-methyl-4-phenyl-1H-imidazol-2-yl](1-methyl-1H-imidazol-2-yl)methyl dimethylcarbamate
Reaktionsgleichung
[CH3:1][N:2]([CH3:35])[C:3](=[O:34])[O:4][CH:5]([C:12]1[N:13]([CH3:33])[C:14]([C:23]2[S:24][C:25]3[N:26]=[CH:27][N:28]=[C:29]([NH2:32])[C:30]=3[N:31]=2)=[C:15]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[N:16]=1)[C:6]1C=CC=CC=1.[CH3:36][N:37]1[CH:41]=[CH:40][N:39]=C1C=O>>[CH3:35][N:2]([CH3:1])[C:3](=[O:34])[O:4][CH:5]([C:12]1[N:13]([CH3:33])[C:14]([C:23]2[S:24][C:25]3[N:26]=[CH:27][N:28]=[C:29]([NH2:32])[C:30]=3[N:31]=2)=[C:15]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[N:16]=1)[C:6]1[N:37]([CH3:36])[CH:41]=[CH:40][N:39]=1Komponenten
3
Edukt 2
Produkt 1
Versuchsvorschrift
The title compound was prepared by a similar process to that described for Intermediate 97 but using 1-methyl-2-imidazolecarboxaldehyde in place of benzaldehyde. Pale yellow oil (33 mg, 46%);