1-Propanone, 3-(dimethylamino)-1-phenyl-, hydrochloride (1:1) → 3-(Dimethylamino)-1-phenyl-1-propanone

HRID 326399

Reaktionsgleichung

Reaktionsgleichung von HRID 326399
Cl.[CH3:2][N:3]([CH3:14])[CH2:4][CH2:5][C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:7].C(=O)(O)[O-].[Na+]>ClCCl>[CH3:14][N:3]([CH3:2])[CH2:4][CH2:5][C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:7]

Komponenten

4

Edukt 2

HCID 928441-Propanone, 3-(dimethylamino)-1-phenyl-, hydrochloride (1:1)HCID 516892Sodium Bicarbonate

Produkt 1

HCID 770423-(Dimethylamino)-1-phenyl-1-propanoneAusbeute 95,3 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

3-Dimethylaminopropiophenone hydrochloride (20 g) was treated with aqueous sodium bicarbonate solution in dichloromethane. The layers were separated and the organic phase was dried over anhydrous magnesium sulfate, filtered, and the filtrate was evaporated to provide 15.8 g of 3-dimethylaminopropiophenone.

Aufarbeitung

  1. customThe layers were separated
  2. dry with materialthe organic phase was dried over anhydrous magnesium sulfate
  3. filtrationfiltered
  4. customthe filtrate was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-8405d6c06e7a480280c47c4f322f1fd8
Quelldatensatz
uspto-grants-1993_12
Patentnummer
US05268468

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