1-(4-(Methylsulfonyl)phenyl)piperazine → (4-(4-(Methylsulfonyl)phenyl)piperazin-1-yl)(2-morpholino-5-nitrophenyl)methanone
Reaktionsgleichung
[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([N:11]2[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]2)=[CH:7][CH:6]=1)(=[O:4])=[O:3].[N:17]1([C:23]2[CH:31]=[CH:30][C:29]([N+:32]([O-:34])=[O:33])=[CH:28][C:24]=2[C:25](Cl)=[O:26])[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1>>[CH3:1][S:2]([C:5]1[CH:6]=[CH:7][C:8]([N:11]2[CH2:16][CH2:15][N:14]([C:25]([C:24]3[CH:28]=[C:29]([N+:32]([O-:34])=[O:33])[CH:30]=[CH:31][C:23]=3[N:17]3[CH2:22][CH2:21][O:20][CH2:19][CH2:18]3)=[O:26])[CH2:13][CH2:12]2)=[CH:9][CH:10]=1)(=[O:3])=[O:4]Komponenten
3
Versuchsvorschrift
The title compound was prepared according to the procedure described for example 46 from 1-(4-Methanesulfonyl-phenyl)-piperazine and 2-Morpholin-4-yl-5-nitro-benzoyl chloride (76%, yellow solid, MS (m/e): 475.1 (M+H, 100%)
Quellen und Nachweise
- ORD-Eintrag
- ord-e6c21f315e2e4ac7b1e762d84458329a
- Quelldatensatz
- uspto-grants-2008_09
- Patentnummer
- US07427612B2
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