Iodine → 2-[2-(Diethylamino)ethyl]-6-phenyl-isothiazolo[5,4-d]pyrimidin-3(2H)-one
Reaktionsgleichung
[CH2:1]([N:3]([CH2:22][CH3:23])[CH2:4][CH2:5][NH:6][C:7]([C:9]1[C:10]([SH:21])=[N:11][C:12]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[N:13][CH:14]=1)=[O:8])[CH3:2].II>>[CH2:22]([N:3]([CH2:1][CH3:2])[CH2:4][CH2:5][N:6]1[C:7](=[O:8])[C:9]2[C:10](=[N:11][C:12]([C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=3)=[N:13][CH:14]=2)[S:21]1)[CH3:23]Komponenten
3
Versuchsvorschrift
Using the procedure of Example 20, 3.3 g (0.01 mol) of 4-mercapto-2-phenyl-pyrimidine-5-carboxylic acid (2-diethylamino-ethyl)-amide (from Preparation 36) and 2.54 g (0.01 mol) of iodine were reacted to give 2.25 g of the title compound after recrystallization from isopropanol, mp 106°-107° C.
Aufarbeitung
- customwere reacted
Quellen und Nachweise
- ORD-Eintrag