Benzoic acid, 2-chloro-5-[(methylamino)sulfonyl]- → Rac-2-(3-hydroxymethyl-pyrrolidin-1-yl)-5-methylsulfamoyl-benzoic acid

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Benzoic acid, 2-chloro-5-[(methylamino)sulfonyl]-	HCID 111724	—
Edukt	(Pyrrolidin-3-yl)methanol	HCID 13400657	—
Edukt	5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid	HCID 59793489	—
Produkt	Rac-2-(3-hydroxymethyl-pyrrolidin-1-yl)-5-methylsulfamoyl-benzoic acid	HCID 59793538	25%

Reaktionsschritte

The title compound was synthesised according to the procedure described for the synthesis of 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid (Example S) from 2-Chloro-5-methylsulfamoyl-benzoic acid and rac-pyrrolidin-3-yl-methanol and obtained in 25% yield. MS (m/e): 313.0 MH− (100%).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07427612B2
Quelldatensatz	uspto-grants-2008_09
ORD ID	ord-cee4307d238e4013ae44af9eac6a34e4
Quellennotiz	uspto-grants-2008_09