Ammonia → 3-Chloro-2-methyl-6-nitroaniline
Reaktionsgleichung
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([Cl:11])[C:3]=1[CH3:12].[NH3:13]>>[Cl:11][C:4]1[C:3]([CH3:12])=[C:2]([NH2:13])[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=1Komponenten
3
Reaktionsbedingungen
- Temperatur
- 130 °C
Versuchsvorschrift
A suspension of 2,6-dichloro-3-nitrotoluene (6.0 g, 29 mmol) in 50% methanolic ammonia (60 mL) was stirred at 130° C. (340 lb pressure) for 18 hours. The autoclave was cooled to -30° C., opened, and the precipitate was filtered off and washed with methanol to give 4.14 g (76%) of 3-chloro-2-methyl-6-nitrobenzenamine.
Aufarbeitung
- temperatureThe autoclave was cooled to -30° C.
- filtrationthe precipitate was filtered off
- washwashed with methanol
Quellen und Nachweise
- ORD-Eintrag
- ord-6a783ee54f534c5382fab3da4c85a8fe
- Quelldatensatz
- uspto-grants-1993_12
- Patentnummer
- US05273975
Notizen zur Reaktion
Wird geladen…