HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
tert-Butyl 4-(bromomethyl)-1H-benzo[d]imidazole-1-carboxylate → 5,6-Dihydro-N,N-dimethyl-4H-pyrrolo(3,2,1ij)quinolin-5-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | tert-Butyl 4-(bromomethyl)-1H-benzo[d]imidazole-1-carboxylate | HCID 15744964 | — |
| Edukt | Diethyl (dipropylamino)propanedioate | HCID 15744966 | — |
| Lösungsmittel | Ether tetrahydrofuran | HCID 21868444 | — |
| Produkt | 5,6-Dihydro-N,N-dimethyl-4H-pyrrolo(3,2,1ij)quinolin-5-amine | HCID 11469718 | — |
Reaktionsschritte
This compound was prepared by following the procedure of Example 18, but substituting methyl 7-(bromomethyl)-1H-indole-1-carboxylate for t-butyl 4-(bromomethyl)-1H-benzimidazole-1-carboxylate and diethyl (dimethylamino)malonte for diethyl (dipropylamino)malonate. The bulk of the product was converted to the maleate salt, mp 114°-115° C. from THF/ether.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05273975 |
| Quelldatensatz | uspto-grants-1993_12 |
| ORD ID | ord-556cf091629349e592814e7e8c44d29f |
| Quellennotiz | uspto-grants-1993_12 |