Oxalic Acid → (+)-3-[4-[N-n-Propyl-N-(5-Methoxychroman-3-Yl)Amino]Butyl]-2,4-Dioxo-3-Azaspiro[4.5]Decane (Oxalate)

HRID 327535Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 327535
[CH3:1][O:2][C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[CH2:5][CH:6]([NH:13][CH2:14][CH2:15][CH2:16][CH2:17][N:18]1[C:22](=[O:23])[C:21]3([CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]3)[CH2:20][C:19]1=[O:29])[CH2:7][O:8]2.[C:30]([OH:35])(=[O:34])[C:31]([OH:33])=[O:32].CO[C:38]1[CH:47]=CC=C2[C:39]=1CC(NCCCCN1C(=O)C3(CCCCC3)CC1=O)CO2.C(O)(=O)C(O)=O>>[C:30]([OH:35])(=[O:34])[C:31]([OH:33])=[O:32].[CH2:39]([N:13]([CH2:14][CH2:15][CH2:16][CH2:17][N:18]1[C:22](=[O:23])[C:21]2([CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]2)[CH2:20][C:19]1=[O:29])[CH:6]1[CH2:5][C:4]2[C:9](=[CH:10][CH:11]=[CH:12][C:3]=2[O:2][CH3:1])[O:8][CH2:7]1)[CH2:38][CH3:47]

Komponenten

4

Edukt 3

HCID 971Oxalic AcidHCID 18966575(+)-3-[4-[N-(5-Methoxychroman-3-Yl)Amino]Butyl]-2,4-Dioxo-3-Azaspiro[4.5]DecaneHCID 18966585(+)-3-{4-[N-(5-Methoxy-3-Chromanyl)Amino]Butyl}-2,4-Dioxo-3-Azaspiro[4.5]Decane Oxalate

Produkt 1

HCID 18966570(+)-3-[4-[N-n-Propyl-N-(5-Methoxychroman-3-Yl)Amino]Butyl]-2,4-Dioxo-3-Azaspiro[4.5]Decane (Oxalate)

Versuchsvorschrift

Using the procedure described in Example 10, but replacing the compound of Example 9 by the compound of Example 28, the product of the title is obtained. It is salified with oxalic acid.

Aufarbeitung

  1. customthe product of the title is obtained

Quellen und Nachweise

ORD-Eintrag
ord-b6c785f341aa40b48e24c4139d28a4c6
Quelldatensatz
uspto-grants-1993_12
Patentnummer
US05273994

Notizen zur Reaktion

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