HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Cyclopropanemethanamine → [2-(Cyclopropylmethyl-amino)-5-methanesulfonyl-phenyl]-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Cyclopropanemethanamine | HCID 75646 | — |
| Edukt | (2-Iodo-5-methanesulfonyl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone | HCID 59793691 | — |
| Produkt | [2-(Cyclopropylmethyl-amino)-5-methanesulfonyl-phenyl]-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone | HCID 68839612 | 40% |
Reaktionsschritte
The title compound was prepared according to the procedure described for example 301 from (2-Iodo-5-methanesulfonyl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone (compound CK) and Cyclopropanemethylamine (40% yield, white foam, MS (m/e): 482.5 (M+H, 100%)
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07427612B2 |
| Quelldatensatz | uspto-grants-2008_09 |
| ORD ID | ord-4de433ffe56143aa8ee1840fef8806a6 |
| Quellennotiz | uspto-grants-2008_09 |