HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(1,1'-Biphenyl)-2-carboxaldehyde → 2,6-Diamino-4-(biphenyl-2-yl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (1,1'-Biphenyl)-2-carboxaldehyde | HCID 121052 | — |
| Edukt | Carbamimidoyl-acetic acid ethyl ester | HCID 4599837 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 2,6-Diamino-4-(biphenyl-2-yl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester | HCID 70631644 | 33% |
Reaktionsschritte
Upon heating a solution of 9.1 g biphenyl-2-aldehyde and 13.0 g amidinoacetic acid ethyl ester in 200 ml ethanol for two hours, 2,6-diamino-4-(biphenyl-2-yl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester of m.p. 215° (ethanol) is obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04016277 |
| Quelldatensatz | uspto-grants-1977_04 |
| ORD ID | ord-cca57af9b6a948d3bc0cac57d86293ef |
| Quellennotiz | uspto-grants-1977_04 |