HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → Propranolol Hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | Propranolol | HCID 4946 | — |
| Lösungsmittel | Diethyl Ether | HCID 3283 | — |
| Produkt | Propranolol Hydrochloride | HCID 62882 | — |
Reaktionsschritte
1-(isopropyl)-3-azetidinol and α-naphthol were reacted in the same manner as in Example 6 to form 1-(α-naphthoxy)-3-(iso-propylamino)-2-propanol. Then the propanol was dissolved in anhydrous ether and was converted to a hydrochloride by blowing a hydrochloric acid gas into the resulting solution. As a result 1-(α-naphthoxy)-3-(isopropylamino)-2-propanol hydrochloride melting at 162°-164° C was obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04018824 |
| Quelldatensatz | uspto-grants-1977_04 |
| ORD ID | ord-77ed6ab9cd424e5b846c165a7ead2e71 |
| Quellennotiz | uspto-grants-1977_04 |