Benzoyl isothiocyanate → N-benzoyl-N'-[2-(2-pyrimidylmethylthio)ethyl]thiourea
Reaktionsgleichung
[NH2:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[N:11]=[CH:10][CH:9]=[CH:8][N:7]=1.[C:12]([N:20]=[C:21]=[S:22])(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[C:12]([NH:20][C:21]([NH:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[N:7]=[CH:8][CH:9]=[CH:10][N:11]=1)=[S:22])(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1Komponenten
3
Versuchsvorschrift
By the procedure of Example 18, 2-[(2-aminoethyl)-thiomethyl]pyrimidine is reacted with benzoyl isothiocyanate to give N-benzoyl-N'-[2-(2-pyrimidylmethylthio)ethyl]thiourea. Removing the benzoyl group by the procedure of Example 18 give N-[2-(2-pyrimidylmethlthio)ethyl]thiourea.
Quellen und Nachweise
- ORD-Eintrag
- ord-da55414c5b324891bbb5fc3d35a388b3
- Quelldatensatz
- uspto-grants-1977_04