Ammonia → 3,5-Dichloro-2-hydroxybenzamide

HRID 329193Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 329193
[Cl:1][C:2]1[CH:11]=[C:10]([Cl:12])[CH:9]=[C:4]([C:5](OC)=[O:6])[C:3]=1[OH:13].[NH3:14]>>[Cl:1][C:2]1[CH:11]=[C:10]([Cl:12])[CH:9]=[C:4]([C:5]([NH2:14])=[O:6])[C:3]=1[OH:13]

Komponenten

3

Edukt 2

HCID 222Ammonia2×HCID 82082Benzoic acid, 3,5-dichloro-2-hydroxy-, methyl ester

Produkt 1

HCID 125631993,5-Dichloro-2-hydroxybenzamide

Reaktionsbedingungen

Temperatur
25 °C

Versuchsvorschrift

A 1 liter Parr autoclave was charged with 221 g. (1 mole) -dichlorophenyl)- of methyl 3,5-dichlorosalicylate and 140 g. (8 moles) of anhydrous ammonia. The mixture was stirred at 25° C for 24 hours. After venting excess ammonia, the product was ground to a fine powder and triturated with boiling chloroform. The mixture was filtered while hot and the residue weighed 153 g. Analysis by infrared, gas chromatography, and nuclear magnetic resonance confirmed that the product was 3,5-dichlorosalicylamide.

Aufarbeitung

  1. additionA 1 liter Parr autoclave was charged with 221 g
  2. customtriturated with boiling chloroform
  3. filtrationThe mixture was filtered while hot and the residue

Quellen und Nachweise

ORD-Eintrag
ord-a66591768d304c25bc90ad70e522d405
Quelldatensatz
uspto-grants-1977_04
Patentnummer
US04020081

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