1-(4-Chlorophenyl)-1-octen-3-one → 1-(4-Chlorophenyl)-3-octanone

HRID 329953

Reaktionsgleichung

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[CH:9][C:10](=[O:16])[CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])=[CH:4][CH:3]=1>[Ni].C1(C)C=CC=CC=1>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][CH2:9][C:10](=[O:16])[CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])=[CH:6][CH:7]=1

Komponenten

Reaktionsbedingungen

Temperatur: 60 °C

Versuchsvorschrift

15 g of Raney nickel are added to a solution of 100 g (0.423 mol) of 1-(4-chlorophenyl)-1-octen-3-one in 500 ml of toluene and the mixture is stirred for 5 hours at 60° C. under a hydrogen pressure of 70-90 bar in an autoclave. After this the reaction mixture is filtered and concentrated under reduced pressure. 97.3 g (96.4% of theory) of 1-(4-chlorophenyl)-3-octanone are obtained in the form of a colorless oil. ##STR36##

Aufarbeitung

filtrationAfter this the reaction mixture is filtered
concentrationconcentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag: ord-e5bf4d7c678448c0b877ea636881a094
Quelldatensatz: uspto-grants-1990_01
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US04894383

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