HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethyl Acetate → (2-Isobutoxy-5-methanesulfonyl-phenyl)-(4-quinolin-2-yl-piperazin-1-yl)-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethyl Acetate | HCID 8857 | — |
| Edukt | 2-Isobutoxy-5-methanesulfonyl-benzoic acid | HCID 23503110 | — |
| Edukt | 2-(Piperazin-1-yl)quinoline hydrochloride | HCID 52988159 | — |
| Lösungsmittel | Acetonitrile | HCID 6342 | — |
| Produkt | (2-Isobutoxy-5-methanesulfonyl-phenyl)-(4-quinolin-2-yl-piperazin-1-yl)-methanone | HCID 11619702 | — |
Reaktionsschritte
Prepared in analogy to example 1.1(b) from 2-piperazin-1-yl-quinoline hydrochloride and 2-isobutoxy-5-methanesulfonyl-benzoic acid (example 2.4) in acetonitrile. Chromatography (SiO2; ethyl acetate) yields the title compound as a yellowish solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07429585B2 |
| Quelldatensatz | uspto-grants-2008_09 |
| ORD ID | ord-c6c8bde8a52c4f579e9081b33a21f958 |
| Quellennotiz | uspto-grants-2008_09 |