Dimethylformamide → (3-Methyl-but-3-enyloxymethyl)-benzene

HRID 332071Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 332071
[CH:1]1[CH:6]=[CH:5][C:4]([CH2:7]Br)=[CH:3][CH:2]=1.[H-].[Na+].CN([CH:14]=[O:15])C>>[CH3:5][C:4](=[CH2:3])[CH2:7][CH2:14][O:15][CH2:7][C:4]1[CH:5]=[CH:6][CH:1]=[CH:2][CH:3]=1

Komponenten

4

Edukt 3

HCID 6228DimethylformamideHCID 7498Benzyl BromideHCID 24758Sodium hydride

Produkt 1

HCID 11095166(3-Methyl-but-3-enyloxymethyl)-benzene

Versuchsvorschrift

BnBr was added to the mixture of alcohol and NaH in DMF cooled in an ice bath. The mixture was stirred at room temperature overnight and the solid was filtered. The solvent was removed and the residue was purified by column chromatography to give compound 1.

Aufarbeitung

  1. temperaturecooled in an ice bath
  2. filtrationthe solid was filtered
  3. customThe solvent was removed
  4. customthe residue was purified by column chromatography

Quellen und Nachweise

ORD-Eintrag
ord-8b3cf9473ad641549a850aaa49a84708
Quelldatensatz
uspto-grants-2014_11
Patentnummer
US08877796B2

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