4-(4-Nitrophenyl)-morpholin-3-ON → 4-(4-Aminophenyl)morpholin-3-one

HRID 33254

Reaktionsgleichung

Reaktionsgleichung von HRID 33254
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:15][CH2:14][O:13][CH2:12][C:11]2=[O:16])=[CH:6][CH:5]=1)([O-])=O>C(OCC)(=O)C.C(O)C>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([N:10]2[CH2:15][CH2:14][O:13][CH2:12][C:11]2=[O:16])=[CH:8][CH:9]=1

Komponenten

4

Edukt 1

HCID 114473754-(4-Nitrophenyl)-morpholin-3-ON

Produkt 1

HCID 111948544-(4-Aminophenyl)morpholin-3-one

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 702EthanolLösungsmittelHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

To a solution of 2.6 g 4-(4-Nitro-phenyl)-morpholin-3-one in 350 ml ethyl acetate and 17 ml ethanol, 13.2 g SnCl2 dihydrate were added and the reaction mixture was heated to reflux for 2 h. Then after cooling to RT the mixture was stirred for 16 h. The precipitated product was collected by filtration and was pure enough for the next reaction step. Yield: 2.07 g.

Aufarbeitung

  1. temperaturethe reaction mixture was heated
  2. temperatureto reflux for 2 h
  3. filtrationThe precipitated product was collected by filtration
  4. customwas pure enough for the next reaction step

Quellen und Nachweise

ORD-Eintrag
ord-2d9233f596b449578394ee61ada102cf
Quelldatensatz
uspto-grants-2008_09
Patentnummer
US07429581B2

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