Trimethylsilyldiazomethane → Methyl 5-formyl-2-furoate

HRID 332587

Reaktionsgleichung

Reaktionsgleichung von HRID 332587
[CH:1]([C:3]1[O:7][C:6]([C:8]([OH:10])=[O:9])=[CH:5][CH:4]=1)=[O:2].[CH3:11][Si](C=[N+]=[N-])(C)C>CC(C)=O>[CH3:11][O:9][C:8]([C:6]1[O:7][C:3]([CH:1]=[O:2])=[CH:4][CH:5]=1)=[O:10]

Komponenten

4

Edukt 2

HCID 167693TrimethylsilyldiazomethaneHCID 27937195-Formyl-2-furancarboxylic Acid

Produkt 1

HCID 12283779Methyl 5-formyl-2-furoate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

5-Formyl-2-furancarboxylic acid (5 g, 35.7 mmol) was dissolved in acetone (100 mL), and trimethylsilyl-diazomethane/2M hexane solution (23.2 mL, 46.4 mmol) was slowly added dropwise at room temperature. After stirring at room temperature for 10 minutes, the solvent was evaporated under reduced pressure to give 5-formyl-2-furancarboxylic acid methyl ester as a crude product.

Aufarbeitung

  1. customthe solvent was evaporated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-f7bcdd8ed3a44b75afc4740aea08f9ad
Quelldatensatz
uspto-grants-2014_11
Patentnummer
US08877805B2

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