HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → (S)-3-(1,3-Dioxolan-2-yl)propyl 2-amino-3-phenylpropanoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- | HCID 77857 | — |
| Edukt | 2-(3-Chloropropyl)-1,3-dioxolane | HCID 552072 | — |
| Lösungsmittel | 1,4-Dioxane | HCID 31275 | — |
| Produkt | (S)-3-(1,3-Dioxolan-2-yl)propyl 2-amino-3-phenylpropanoate | HCID 71113124 | — |
Reaktionsschritte
The title compound was prepared in two steps. Boc-Phe-OH was reacted with 2-(3-chloropropyl)-1,3-dioxolane according to Example 10 Step 1, and the subsequent product reacted with hydrogen chloride in dioxan according to Example 79 Step 5.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08877774B2 |
| Quelldatensatz | uspto-grants-2014_11 |
| ORD ID | ord-981eb4ca7d664fe68fd01923aa795e02 |
| Quellennotiz | uspto-grants-2014_11 |