Triphenylstannane → HCID 11152734, Verbindung

HRID 333641

Reaktionsgleichung

Reaktionsgleichung von HRID 333641
C1(C)C(C)=CC=CC=1.C1([SnH](C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[C:28]([C:31]1[CH:36]=[CH:35][C:34]([N:37]=[N:38][C:39](=[C:43]2[C:52]3[C:47](=[CH:48][CH:49]=[CH:50][CH:51]=3)[CH2:46][C:45]([CH3:54])([CH3:53])[NH:44]2)[C:40]([NH2:42])=[O:41])=[CH:33][CH:32]=1)(=[O:30])[CH3:29]>C(#N)C>[C:28]([C:31]1[CH:32]=[CH:33][C:34]([N:37]=[N:38][CH:39]([CH:43]2[C:52]3[C:47](=[CH:48][CH:49]=[CH:50][CH:51]=3)[CH2:46][C:45]([CH3:54])([CH3:53])[NH:44]2)[C:40]([NH2:42])=[O:41])=[CH:35][CH:36]=1)(=[O:30])[CH3:29]

Komponenten

5

Edukt 3

HCID 6460TriphenylstannaneHCID 7237O-XyleneHCID 178466770HCID 178466770, Verbindung

Produkt 1

HCID 11152734HCID 11152734, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6342AcetonitrileLösungsmittel

Versuchsvorschrift

In a nitrogen atmosphere, 2-(4-acetyl-phenylazo)-2-(3,3-dimethyl-3,4-dihydro-2H-isoquinoline-1-ylidene)-acetamide (Asinex Corp., Russia) is dissolved in acetonitrile, and the obtained product is added with xylene in which triphenyl tin hydride (Aldrich, Corp., USA) is dissolved, and the mixture is refluxed. The refluxed product is cooled to room temperature and an insoluble matter is separated by filtration. The solvent is removed from the filtrate by reducing the pressure. The residue containing the reaction product is purified by column chromatography to obtain the title compound.

Aufarbeitung

  1. dissolutionis dissolved
  2. temperaturethe mixture is refluxed
  3. customan insoluble matter is separated by filtration
  4. customThe solvent is removed from the filtrate
  5. additionThe residue containing the reaction product
  6. customis purified by column chromatography

Quellen und Nachweise

ORD-Eintrag
ord-ce31b888ce6146548f9a61256b784f0d
Quelldatensatz
uspto-grants-2014_11
Patentnummer
US08883504B2

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