1-Bromo-4-fluoro-2-iodobenzene → 5-Fluoro-methyl-benzofuran-3-carboxylic acid
Reaktionsgleichung
Br[C:2]1[CH:7]=[CH:6][C:5]([F:8])=[CH:4][C:3]=1I.BrC1C=CC2[O:18][C:17]([CH3:19])=[C:16]([C:20]([OH:22])=[O:21])C=2C=1>>[F:8][C:5]1[CH:6]=[CH:7][C:2]2[O:18][C:17]([CH3:19])=[C:16]([C:20]([OH:22])=[O:21])[C:3]=2[CH:4]=1Komponenten
3
Versuchsvorschrift
This intermediate was prepared from 1-bromo-4-fluoro-2-iodo-benzene in two steps according to the preparation of 5-bromo-methyl-benzofuran-3-carboxylic acid (from 1,4-dibromo-2-iodo-benzene).
Quellen und Nachweise
- ORD-Eintrag
- ord-05bca94a70774e0ea703b0222e71d526
- Quelldatensatz
- uspto-grants-2014_11
- Patentnummer
- US08883789B2
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