HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(1,1'-Biphenyl)-2-carboxaldehyde → 1-(Biphenyl-2-ylmethyl)-4-(2-isopropylphenyl)piperazine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (1,1'-Biphenyl)-2-carboxaldehyde | HCID 121052 | — |
| Edukt | 1-(2-Isopropylphenyl)piperazine | HCID 3608822 | — |
| Edukt | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Edukt | 1-(Biphenyl-2-ylmethyl)-4-phenylpiperazine | HCID 71602523 | — |
| Produkt | 1-(Biphenyl-2-ylmethyl)-4-(2-isopropylphenyl)piperazine | HCID 71678343 | — |
Reaktionsschritte
100 mg of the target compound (0.27 mmol, 49.1%) was obtained using 1-(2-isopropylphenyl)piperazine (223 mg, 1.09 mmol), biphenyl-2-carbaldehyde (100 mg, 0.55 mmol) and NaBH(OAc)3 (355 mg, 1.65 mmol) according to the synthesis method of Compound 1.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08883796B2 |
| Quelldatensatz | uspto-grants-2014_11 |
| ORD ID | ord-433ba77554b646d7b7dc81591e08f6bd |
| Quellennotiz | uspto-grants-2014_11 |