4-Aminobenzamide → 4-((4-(4-Chlorophenyl)pyrimidin-2-yl)amino)benzamide

Beteiligte Stoffe

Reaktionsschritte

To a solution of 4-(4-chlorophenyl)-2-(methylsulfonyl)pyrimidine (0.10 g, 0.37 mmol) and 4-aminobenzamide in 2-propanol (3 ml) was heated to 120° C. in a sealed vessel for 14 hours. The crude material was concentrated and purified by preparative HPLC to provide the title compound as a beige solid: LC/MS Retention Time; 6.30 min (Method A), M+1; 325.

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