Triethylamine → 1-[2-(2,6-Diethyl-4-methylphenyl)-2-oxoacetyl]-1-methyl-2-(1-methylethylidene)hydrazine

HRID 335409

Reaktionsgleichung

[CH3:1][NH:2][N:3]=[C:4]([CH3:6])[CH3:5].C(N(CC)CC)C.[CH2:14]([C:16]1[CH:21]=[C:20]([CH3:22])[CH:19]=[C:18]([CH2:23][CH3:24])[C:17]=1[C:25](=[O:29])[C:26](Cl)=[O:27])[CH3:15]>C(#N)C>[CH2:14]([C:16]1[CH:21]=[C:20]([CH3:22])[CH:19]=[C:18]([CH2:23][CH3:24])[C:17]=1[C:25](=[O:29])[C:26]([N:2]([CH3:1])[N:3]=[C:4]([CH3:6])[CH3:5])=[O:27])[CH3:15]

Komponenten

Reaktionsbedingungen

Temperatur: 1 °C

Versuchsvorschrift

To a 1000 ml volume four-necked flask, 1-methyl-2-(2-propylidene)hydrazine (17-a) (9.61 g), acetonitrile (280 ml), and triethylamine (17 ml) were added under a nitrogen atmosphere and cooled to about 1° C. To the mixture, 2-(2,6-diethyl-4-methylphenyl)-2-oxoacetyl chloride (6-a) (27.12 g) dissolved in acetonitrile (77 ml) was added dropwise over 30 minutes.

Aufarbeitung

additionwas added dropwise over 30 minutes

Quellen und Nachweise

ORD-Eintrag: ord-32796de4843940589233da3d6cd68bbe
Quelldatensatz: uspto-grants-2014_11
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08884010B2

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