HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-chloro-6-(trifluoromethyl)-1H-benzimidazole → HCID 178515615, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-chloro-6-(trifluoromethyl)-1H-benzimidazole | HCID 337905 | — |
| Edukt | 8-Amino-1,2,3,4-tetrahydronaphthalen-2-ol | HCID 23066995 | — |
| Produkt | HCID 178515615 | HCID 178515615 | — |
Reaktionsschritte
The reaction of 2-chloro-6-(trifluoromethyl)-1H-benzo[d]imidazole (154 mg, 0.7 mol, prepared according to the procedure described in WO 2004/035549 A1) with 8-amino-1,2,3,4-tetrahydronaphthalen-2-ol (83 mg, 0.5 mmol, prepared according to the procedure described in WO 2003/095420 A1) under the condition of Example 21(b) afforded the title compound. MS (ESI, pos. ion) m/z: 348 (M+1).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07429608B2 |
| Quelldatensatz | uspto-grants-2008_09 |
| ORD ID | ord-df4cc9f17397431eac6bea5953beae6f |
| Quellennotiz | uspto-grants-2008_09 |