3-Methyl-2,4-pentanedione → 3-hydroxy-4-(3,4,5-trimethyl-1H-pyrazol-1-yl)phenyl acetate

HRID 337362

Reaktionsgleichung

Reaktionsgleichung von HRID 337362
[CH3:1][C:2]1[CH:7]=[CH:6]C(S(O)(=O)=O)=[CH:4][CH:3]=1.[C:12]([O:15][C:16]1[CH:21]=[CH:20][C:19]([NH:22][NH2:23])=[C:18]([OH:24])[CH:17]=1)(=[O:14])[CH3:13].C(OC1C=CC(N)=C(O)C=1)(=O)C.CC(C(=O)C)C(=O)C>>[C:12]([O:15][C:16]1[CH:21]=[CH:20][C:19]([N:22]2[C:7]([CH3:6])=[C:2]([CH3:1])[C:3]([CH3:4])=[N:23]2)=[C:18]([OH:24])[CH:17]=1)(=[O:14])[CH3:13]

Komponenten

4

Edukt 3

HCID 699493-Methyl-2,4-pentanedioneHCID 197705154-Amino-3-hydroxyphenyl acetateHCID 867032644-Hydrazinyl-3-hydroxyphenyl acetate 4-methylbenzenesulfonate

Produkt 1

HCID 867032673-hydroxy-4-(3,4,5-trimethyl-1H-pyrazol-1-yl)phenyl acetateAusbeute 52,2 %

Versuchsvorschrift

230 mg of the title compound was prepared in a manner similar to Example 54b) by using 4-hydrazinyl-3-hydroxyphenyl acetate 4-methylbenzenesulfonate (0.6 g), which was prepared from 4-amino-3-hydroxyphenyl acetate (1.0 g) in a manner similar to Example 54a), and 3-methylpentane-2,4-dione (1.0 g).

Quellen und Nachweise

ORD-Eintrag
ord-5ca467def39e42dd87202fabc8caaa62
Quelldatensatz
uspto-grants-2014_11
Patentnummer
US08889727B2

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