Pyrazole → 2,2-dimethyl-1-(1-methyl-1H-pyrazol-5-yl)Cyclopentanol

Beteiligte Stoffe

Reaktionsschritte

The reaction and aftertreatment were conducted in the same manner as in Example 8a by using pyrazole (3.70 g, 45.1 mmol), n-butyl lithium (2.69 M solution in hexane; 17 mL, 45.7 mmol), 2,2-dimethylcyclopentanone (5.00 g, 44.6 mmol) and THF (100 mL), to yield the title compound (630 mg, 7.3%) as a colorless solid.

Herkunft & Nachweise