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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 337911Erstellt: 25. Oktober 2026

Potassium Carbonate → HCID 89963326, Verbindung

https://huagongshe.com/reaction/337911

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktPotassium CarbonateHCID 11430—
Edukt2,4-DifluoropyrimidineHCID 137716—
EduktHCID 89963518HCID 89963518—
LösungsmittelDimethylformamideHCID 6228—
ProduktHCID 89963326HCID 8996332670,2%

Reaktionsschritte

The reaction and aftertreatment were conducted in the same manner as in Example 111d by using the 2-fluoro-4-{[(1S*,2R*)-2-(1-methyl-1H-pyrazol-5-yl)cyclopentyl]oxy}benzenesulfonamide (0.16 g, 0.47 mmol) prepared in Example 114c, 2,4-difluoropyrimidine (0.16 g, 1.41 mmol), potassium carbonate (0.26 g, 1.88 mmol) and DMF (4.7 mL), to yield the title compound (143.6 mg, 70%) as a colorless amorphous solid.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08889741B2
Quelldatensatzuspto-grants-2014_11
ORD IDord-d65347fd72d34332b2542c5cfc22c51f
Quellennotizuspto-grants-2014_11