Sodium Hydroxide → HCID 59797443, Verbindung

HRID 33800Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 33800
C[O:2][C:3](=[O:33])[CH2:4][O:5][C:6]1[C:19]2[S:18][C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[S:11][C:10]=2[C:9]([C:20]2[O:21][C:22]([N:27]3[CH2:32][CH2:31][O:30][CH2:29][CH2:28]3)=[CH:23][C:24](=[O:26])[CH:25]=2)=[CH:8][CH:7]=1.[OH-].[Na+:35]>CO>[Na+:35].[N:27]1([C:22]2[O:21][C:20]([C:9]3[C:10]4[S:11][C:12]5[C:17](=[CH:16][CH:15]=[CH:14][CH:13]=5)[S:18][C:19]=4[C:6]([O:5][CH2:4][C:3]([O-:33])=[O:2])=[CH:7][CH:8]=3)=[CH:25][C:24](=[O:26])[CH:23]=2)[CH2:32][CH2:31][O:30][CH2:29][CH2:28]1

Komponenten

4

Edukt 2

HCID 14798Sodium HydroxideHCID 59797432[4-(6-Morpholin-4-yl-4-oxo-4H-pyran-2-yl)-thianthren-1-yloxy]-acetic acid methyl ester

Produkt 1

HCID 59797443HCID 59797443, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

To a solution of [4-(6-Morpholin-4-yl-4-oxo-4H-pyran-2-yl)-thianthren-1-yloxy]-acetic acid methyl ester (1.41 g, 2.91 mmol) in anhydrous methanol (10 ml) was added sodium hydroxide (120 mg, 2.91 mmol) in a single portion. The solution was then stirred at room temperature for 24 hours whereupon the solvent was removed in vacuo to give the title compound as an off white paste (1.43 g, 98%) that required no further purification. m/z (LC-MS, ESP): RT=3.79 min, (M−−23)=468

Aufarbeitung

  1. customwas removed in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-e52a91aebc534d4dacbd50f3f2e5e93f
Quelldatensatz
uspto-grants-2008_09
Patentnummer
US07429660B2

Notizen zur Reaktion

Wird geladen…