HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 338787Erstellt: 23. Oktober 2026
3,5-Dibromo-4-Hydroxybenzaldehyde → 2,6-Dibromo-4-(5-(trifluoromethyl)benzo[d]thiazol-2-yl)phenol
https://huagongshe.com/de/reaction/338787
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | 3,5-Dibromo-4-Hydroxybenzaldehyde | HCID 18100 | — |
| Edukt | 2-Amino-4-(trifluoromethyl)benzenethiol | HCID 88042 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 2,6-Dibromo-4-(5-(trifluoromethyl)benzo[d]thiazol-2-yl)phenol | HCID 136183494 | — |
Reaktionsschritte
In a N,N-dimethylformamide (DMF) solvent, a suspension of 3,5-dibromo-4-hydroxybenzaldehyde (1.0 eq.) and 2-amino-4-(trifluoromethyl)benzenethiol (1.0 eq.) was heated at a temperature of 100° C. After cooling, DMF was removed therefrom under reduced pressure. Methylene chloride was added to the resultant solid, and the produced precipitate was filtered, and washed with methylene chloride to obtain a solid target product.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US08889881B2 |
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| Quelldatensatz | uspto-grants-2014_11 |
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| ORD ID | ord-b681226bcc2444e1987d034dffcf3148 |
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| Quellennotiz | uspto-grants-2014_11 |
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