Formamide → N-((4-(Benzyloxy)phenyl)(tosyl)methyl)formamide

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

A mixture of 4-methylbenzenesulfinic acid (3.1 g, 19.9 mmol), 4-(benzyloxy)benzaldehyde (4.2 g, 19.9 mmol), and formamide (4.5 mL ) was heated at 60° C. for 20 h. The mixture was diluted with methanol and stirring was continued for 1 h at rt. The resultant solid was filtered and dried to give 3.81 g (49%) of a white solid. The product was used in the next step without future purification.

Herkunft & Nachweise