(3R)-3-amino-3-phenylpropanoic acid → L-Phenylalanine
Reaktionsgleichung
N[C@@H:2]([CH2:9][C:10]([OH:12])=[O:11])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[NH2:13][C@H](CC(O)=O)C1C=CC=CC=1>>[NH2:13][C@H:9]([C:10]([OH:12])=[O:11])[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1Komponenten
3
Versuchsvorschrift
The optical purity of (S)-β-phenylalanine was calculated from the peak area of the chromatogram obtained under analysis conditions illustrated in (1) above. Furthermore, the reaction yield of (S)-β-phenylalaninewas calculated from the peak area of the chromatogram obtained under analysis conditions illustrated in (2) above. Concretely, when the reaction solution contained a solid of β-phenylalanine or a solid of L-phenylalanine, a solution obtained by collecting a part of the reaction solution containing these solids, mixing with a 0.2 mol/l hydrochloric acid solution and dissolving these solids was analyzed. The amount (g) of (S)-β-phenylalanine synthesized was calculated from the peak area of the chromatogram using a calibration curve of (S)-β-phenylalanine standards to determine the yield from (Formula 1). Yield (%)=Amount of (S)-β-phenylalanine synthesized (g)/Amount of L-phenylalanine added (g)×100 (Formula 1)