HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
p-Anisoyl chloride → 4-methoxy-N-[4-(6-methylimidazo[1,2-a]pyridin-2-yl)phenyl]benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | p-Anisoyl chloride | HCID 7477 | — |
| Edukt | 4-(6-Methylimidazo[1,2-a]pyridin-2-yl)aniline | HCID 821084 | — |
| Edukt | Dichloromethane methanol | HCID 21226129 | — |
| Lösungsmittel | Pyridine | HCID 1049 | — |
| Produkt | 4-methoxy-N-[4-(6-methylimidazo[1,2-a]pyridin-2-yl)phenyl]benzamide | HCID 42737530 | 79,3% |
Reaktionsschritte
Prepared as described in the Amide Coupling section using 4-(6-methylimidazo[1,2-a]pyridin-2-yl)aniline (70 mg, 0.314 mmol) and 4-methoxybenzoyl chloride (54 mg, 0.314 mmol) in dry pyridine (5 ml) to give the title compound (89 mg, 79%) as a pale yellow solid after work-up and flash chromatography (15:1 DCM/MeOH).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08895313B2 |
| Quelldatensatz | uspto-grants-2014_11 |
| ORD ID | ord-f32acd5a5cf7436caa612378691cafef |
| Quellennotiz | uspto-grants-2014_11 |