HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Methoxy-4-nitrobenzaldehyde → 2-Hydroxy-4-nitrobenzaldehyde
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Methoxy-4-nitrobenzaldehyde | HCID 2759599 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Lösungsmittel | Boron tribromide | HCID 25134 | — |
| Produkt | 2-Hydroxy-4-nitrobenzaldehyde | HCID 75570 | 78% |
Reaktionsschritte
Prepared as described in the Demethylation section above using 2-methoxy-4-nitrobenzaldehyde (1.0 g, 5.52 mmol) in dry DCM (25 ml) and BBr3 in DCM (1.0 M, 16 ml, 16 mmol) to give the title compound (0.70 g, 78%) as tan plates after recrystallisation from EtOH.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08895313B2 |
| Quelldatensatz | uspto-grants-2014_11 |
| ORD ID | ord-8c1625e8d0ab443193ea50f7d0b0a35b |
| Quellennotiz | uspto-grants-2014_11 |