HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Isopropylpiperazine → HCID 178436930, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Isopropylpiperazine | HCID 78013 | — |
| Edukt | HCID 178436919 | HCID 178436919 | — |
| Produkt | HCID 178436930 | HCID 178436930 | 19,2% |
Reaktionsschritte
The title compound was prepared from (5-chloropyrazin-2-yl)(2-(6-(2-ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazol-3-yl)-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (80 mg, 154 μmol) and 1-isopropyl-piperazine, (40 mg, 308 μmol) using the method of Example 32. The crude material was purified by HPLC Method D to afford (18 mg, 19%) of the title compound as off-white solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08895544B2 |
| Quelldatensatz | uspto-grants-2014_11 |
| ORD ID | ord-b11d2da0e28b499cb125f5dbae538a33 |
| Quellennotiz | uspto-grants-2014_11 |