Hydrochloric Acid → HCID 178418440, Verbindung

Beteiligte Stoffe

Reaktionsschritte

To a solution of 2 L of concentrated HCl and 1 L of water is added 300 g of the disulfate salt of 2,7-diamino-6-phenylpyrido[2,3-d]pyrimidine and the resulting mixture refluxed with stirring overnight. The reaction mixture is cooled in an ice bath, filtered, and the insoluble product washed with water, followed by ethanol to give 149 g of the title compound 2-amino-6-phenyl-pyrido[2,3-d]pyrimidin-7-ol, mp 390°-395° C. (darkens slowly above 350° C.).

Herkunft & Nachweise