(5-Azidomethyl-furan-2-ylmethyl)-carbamic Acid Tert-Butyl Ester → HCID 60035026, Verbindung

HRID 34106Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 34106
[C:1]([O:5][C:6](=[O:18])[NH:7][CH2:8][C:9]1[O:10][C:11]([CH2:14][N:15]=[N+]=[N-])=[CH:12][CH:13]=1)([CH3:4])([CH3:3])[CH3:2]>C(O)C.[Pd].CC([O-])=O.CC([O-])=O.[Pb+2]>[C:1]([O:5][C:6](=[O:18])[NH:7][CH2:8][C:9]1[O:10][C:11]([CH2:14][NH2:15])=[CH:12][CH:13]=1)([CH3:4])([CH3:2])[CH3:3]

Komponenten

4

Edukt 1

HCID 60053847(5-Azidomethyl-furan-2-ylmethyl)-carbamic Acid Tert-Butyl Ester

Produkt 1

HCID 60035026HCID 60035026, VerbindungAusbeute 101,9 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 131709914Lindlars catalystKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

To a solution of 88.6 mg of (5-azidomethyl-furan-2-ylmethyl)-carbamic acid tert-butyl ester in 3 mL of ethanol was added 30 mg of Lindlar catalyst, stirred at room temperature under hydrogen atmosphere for 15 hours, the catalyst filtered off, and the solvent was evaporated, to afford 81 mg of the title compound as a colorless oil.

Aufarbeitung

  1. filtrationthe catalyst filtered off
  2. customthe solvent was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-c1cd73bbdc5141dab72dbd3f5b96d8e6
Quelldatensatz
uspto-grants-2008_09
Patentnummer
US07429609B2

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