Hydrochloric Acid → HCID 86753552, Verbindung

HRID 342423

Reaktionsgleichung

Reaktionsgleichung von HRID 342423
[CH3:1][C:2]1[O:6][C:5]2[C:7]([N+:11]([O-:13])=[O:12])=[CH:8][CH:9]=[CH:10][C:4]=2[CH:3]=1.[Cl-].[Al+3].[Cl-].[Cl-].[CH3:18][O:19]C(Cl)Cl.Cl>ClCCl>[CH:18]([C:3]1[C:4]2[CH:10]=[CH:9][CH:8]=[C:7]([N+:11]([O-:13])=[O:12])[C:5]=2[O:6][C:2]=1[CH3:1])=[O:19]

Komponenten

6

Edukt 4

HCID 313Hydrochloric AcidHCID 21004Methane, dichloromethoxy-HCID 6451240Aluminum(III) ChlorideHCID 132018972-Methyl-7-nitrobenzofuran

Produkt 1

HCID 86753552HCID 86753552, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel2×

Versuchsvorschrift

To a mixture of 2-methyl-7-nitrobenzo[b]furan (1.77 g) and aluminum chloride (2.66 g) in dichloromethane (40 ml) was added dropwise a solution of dichloromethyl methyl ether (3.6 ml) in dichloromethane (10 ml). The mixture was stirred at ambient temperature for 30 minutes and the reaction mixture was poured into a mixture of ice and 1N-hydrochloric acid. The separated oil was extracted with dichloromethane and the extract was washed with brine, aqueous saturated sodium bicarbonate and brine. Then, the solution was dried over sodium sulfate and evaporated in vacuo. The obtained oil was crystallized from diethyl ether to give 3-formyl-2-methyl-7-nitrobenzo[b]furan (1.83 g).

Aufarbeitung

  1. extractionThe separated oil was extracted with dichloromethane
  2. washthe extract was washed with brine, aqueous saturated sodium bicarbonate and brine
  3. dry with materialThen, the solution was dried over sodium sulfate
  4. customevaporated in vacuo
  5. customThe obtained oil was crystallized from diethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-02a255bdb6784c9caf126c55bafac015
Quelldatensatz
uspto-grants-1999_01
Patentnummer
US05858995

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