Ethanol → 2-(6-Methyl-1H-indol-3-yl)ethan-1-amine

HRID 343451Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 343451
[CH3:1][C:2]1[C:10](Br)=[C:9]2[C:5]([C:6]([CH2:12][CH2:13][NH2:14])=[CH:7][NH:8]2)=[CH:4][CH:3]=1.C(O)C>C(N(CC)CC)C>[CH3:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([CH2:12][CH2:13][NH2:14])=[CH:7][NH:8]2)=[CH:4][CH:3]=1

Komponenten

4

Edukt 2

HCID 702EthanolHCID 15274383HCID 15274383, Verbindung

Produkt 1

HCID 1900062-(6-Methyl-1H-indol-3-yl)ethan-1-amine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8471TriethylamineLösungsmittel

Versuchsvorschrift

A sample of 6-methyl-7-bromo-1 H-indole-3-ethanamine was contacted with Pd/C H2 in the presence of ethanol and triethylamine. The resulting material was evaporated and partitioned between base/CHCl3. The organic phase was dried, concentrated, and dried. The resulting material was taken up into methanol and added to ethereal HCl. The resulting material was washed and vacuum dried.

Aufarbeitung

  1. customThe resulting material was evaporated
  2. custompartitioned between base/CHCl3
  3. customThe organic phase was dried
  4. concentrationconcentrated
  5. customdried
  6. additionadded to ethereal HCl
  7. washThe resulting material was washed
  8. customvacuum dried

Quellen und Nachweise

ORD-Eintrag
ord-63cb0fb11e5e404dbf2452123b65fdb4
Quelldatensatz
uspto-grants-1999_01
Patentnummer
US05861425

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