Methyl iodide → 1-Methyl-3-(5-methyloxazol-2-yl)-pyridinium iodide

HRID 344693Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 344693
[CH3:1][C:2]1[O:6][C:5]([C:7]2[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=2)=[N:4][CH:3]=1.[I:13][CH3:14]>C(O)C>[I-:13].[CH3:14][N+:9]1[CH:10]=[CH:11][CH:12]=[C:7]([C:5]2[O:6][C:2]([CH3:1])=[CH:3][N:4]=2)[CH:8]=1

Komponenten

4

Edukt 2

HCID 6328Methyl iodideHCID 196125075-Methyl-2-(3-pyridyl)-oxazole

Produkt 1

HCID 679250801-Methyl-3-(5-methyloxazol-2-yl)-pyridinium iodide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

5 g of 3-(5-methyloxazol-2-yl)-pyridine prepared as indicated in Chimica Therap 4, 437 (1973) is dissolved in 50 cm3 of ethanol, 3 cm3 of iodomethane is added and the whole is heated under reflux for 10 hours. After cooling and decanting, ether is added, and after filtering, 8.68 g of product is obtained. M.p.=147°-148° C., after crystallization from ethanol.

Aufarbeitung

  1. temperaturethe whole is heated
  2. temperatureunder reflux for 10 hours
  3. temperatureAfter cooling
  4. customdecanting
  5. additionether is added
  6. filtrationafter filtering

Quellen und Nachweise

ORD-Eintrag
ord-51fd0243d6b04062a1810d51847ac00e
Quelldatensatz
uspto-grants-1991_10
Patentnummer
US05053416

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