4-Carbethoxycinnamic acid → 4-Ethoxycarbonylbenzenepropanoic acid
Reaktionsgleichung
[C:1]([C:6]1[CH:16]=[CH:15][C:9]([CH:10]=[CH:11][C:12]([OH:14])=[O:13])=[CH:8][CH:7]=1)([O:3][CH2:4][CH3:5])=[O:2]>CCO.[Rh]>[CH2:4]([O:3][C:1]([C:6]1[CH:16]=[CH:15][C:9]([CH2:10][CH2:11][C:12]([OH:14])=[O:13])=[CH:8][CH:7]=1)=[O:2])[CH3:5]Komponenten
4
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
A solution of 4-carbethoxycinnamic acid (4.9 g) in EtOH (120 ml) was hydrogenated over 5% Rh/C (485 mg) at atmospheric pressure for 21 hr. The solution was filtered and stripped. The residue was crystallized from cyclohexane to afford 2.23 g (46%) of the title compound as white crystals; mp 108.5°-110.5°.
Aufarbeitung
- filtrationThe solution was filtered
- customThe residue was crystallized from cyclohexane
Quellen und Nachweise
- ORD-Eintrag
- ord-ece937894f644ec9864f6d6f677afbf5
- Quelldatensatz
- uspto-grants-1991_10
- Patentnummer
- US05055450
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