HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4,5-Dichloro-2-fluoroaniline → 4-[(3,4-Dichloro-6-fluorophenyl)amino]-7-fluoro-6-nitroquinazoline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4,5-Dichloro-2-fluoroaniline | HCID 223091 | — |
| Edukt | 4-Chloro-7-fluoro-6-nitroquinazoline | HCID 10609358 | — |
| Lösungsmittel | Isopropanol | HCID 3776 | — |
| Produkt | 4-[(3,4-Dichloro-6-fluorophenyl)amino]-7-fluoro-6-nitroquinazoline | HCID 11176185 | 78% |
Reaktionsschritte
3,4-Dichloro-6-fluoroaniline (1 equivalent) was reacted with 4-chloro-7-fluoro-6-nitroquinazoline (3.5 equivalents), in iso-propylalcohol. After filtration, 4-[(3,4-dichloro-6-fluorophenyl)amino]-7-fluoro-6-nitroquinazoline was obtained in 78% yield.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07172749B2 |
| Quelldatensatz | uspto-grants-2007_02 |
| ORD ID | ord-1042ad855505453485b72441af00c3ae |
| Quellennotiz | uspto-grants-2007_02 |