HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Diisopropylethylamine → 1-[7-(3-Fluoro-benzyloxy)-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl]-2-methoxy-ethanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Diisopropylethylamine | HCID 81531 | — |
| Edukt | Methoxyacetyl chloride | HCID 96623 | — |
| Edukt | 7-(3-fluoro-benzyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine hydrochloride | HCID 21080184 | — |
| Produkt | 1-[7-(3-Fluoro-benzyloxy)-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl]-2-methoxy-ethanone | HCID 11772273 | 98% |
Reaktionsschritte
The title compound was prepared in analogy to Example 1 d) from 7-(3-fluoro-benzyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine hydrochloride [Example 1c)] and methoxy-acetic acid chloride with N-ethyl-diisopropylamine as the base. Yield: 98% of theory as a colourless oil; MS: m/e=344 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07173023B2 |
| Quelldatensatz | uspto-grants-2007_02 |
| ORD ID | ord-b968ccedd0584457b42b4a3c19d603ac |
| Quellennotiz | uspto-grants-2007_02 |